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Senior Director, Strategy, Oncology R&D

Location Waltham, Massachusetts, United States Job ID R-228691 Date posted 09/06/2025

Senior Director, Strategy, Oncology R&D

Location: Waltham, MA

Do you have a strategic mindset, analytical rigor, and people leadership that enables you to deliver positive outcomes on high-impact and complex strategic topics? Are you looking to demonstrate those skills to help lead the team that shapes our future oncology strategy and portfolio? 

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company and our innovative medicines are used by millions of patients worldwide. This is the place to make an impact. Here we ensure everyone can reach their full potential, perform at their best and make a valued contribution to the enterprise. 

Within Oncology R&D, we are empowered to be bold, take calculated risks and use our intelligence and courage to always follow the science. This approach has enabled us to successfully deliver 7 new Oncology medicines in as many years. 

It is the breadth and strength of our innovative pipeline that offers both security and stability. And with the goal to deliver 6 new molecular entities by 2025, it’s up to each of us to keep pushing our industry-leading Oncology pipeline forward and build the future. 

Oncology Strategy, Business Development & Alliances Team 

Our team sits at the center of Oncology R&D – driving our R&D strategy and addressing the unmet needs and future focus of AstraZeneca’s oncology pipeline. We operate both internally and externally, leading collaboration and acquisition opportunities as well as partnering closely with external alliances.  

Responsibilities: 

In this role, you will be accountable for the development and delivery of Therapeutic Area Strategy for a defined set of tumours based on our latest priorities.  

What you will do: Deliver end-to-end Tumor Strategy, including: 

  • Clear understanding and prioritization of current and future unmet needs 

  • Tumor-level strategic vision for both near-term and long-term 

  • Integrated clinical strategy across all assets within the same tumor 

  • Competitive early pipeline / long-term portfolio 

  • Above-asset initiatives (e.g., Translational Medicine, Precision Medicine, Data Sciences) 

How you will operate:

  • Lead the Tumor Council to define priorities and deliverables of Tumor Strategy 

  • Develop clear strategic framework /structure to guide teams through complex strategies 

  • Lead and collaborate with cross-functional teams to develop tumor strategy content (e.g., GPTs, Clinical Development, Discovery, BD, Lifecycle and Pipeline, Competitive Intelligence)  

  • Provide strategic counselling to Global Clinical Strategy Head (GCSH) and other senior leaders 

Basic Qualifications:

  • BA/BS and over 8 years of combined experience in life sciences or consulting firm with focus in life science programs or experience working in research, and/or with data, analysis and fact-based decision-making

  • OR MS/MBA and over 5 years of combined experience in life sciences or consulting firm with focus in life science programs or experience working in research, and/or with data, analysis and fact-based decision-making

  • OR PhD or MD and 5 years of combined experience in life sciences or consulting firm with focus in life science programs or experience working in research, and/or with data, analysis and fact-based decision-making

  • Ability to interact and communicate effectively with senior executive teams.

  • Demonstrated ability to lead and influence experienced professionals.

  • Ability to think critically, creatively and to anticipate and solve problems.

  • Ability to navigate and be successful in a fast-paced, highly-matrixed work environment

Preferred Qualifications:

  • Strong analytical and communication skills

  • Effective interpersonal and relationship management skills with consultative approach and ability to interact and build trust

  • Operational effectiveness, highly organized process with follow through

  • Strong initiative to understand our core business goals and establish processes or programs to set direction, generate alignment and push forward

  • Financial background and understanding of forecasts, budgets, financial activities and tools

  • Resourceful, motivated, influential and proactive; able to prioritize in a fast-growing organization

  • Experience in strategic planning processes and tools

  • Scientific background

  • Understanding of the pharmaceutical business (including R&D)

  • Experience in translating business needs into a coordinated plan from cross-functional senior leadership team

  • Ability to develop creative and simple solutions to complex problems

As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026.Find out more information here: Kendall Square Press Release

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

10000136 G CNBM R&D Oncology

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.